Neurological Involvement in Primary Sjögren Syndrome: A Focus on Central Nervous System

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Neurological Involvement in Primary Sjögren Syndrome: A Focus on Central Nervous System

OBJECTIVES Sjögren syndrome is an autoimmune disease involving mainly salivary and lacrimal glands. Beyond widely described PNS involvement, high variable prevalence of CNS manifestations ranging from 2.5 and 60% of all pSS patients has been reported, without specific syndrome definition. The aim of this cohort study was to evaluate the prevalence of CNS signs and symptoms in pSS patients and t...

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Primary Sjögren Syndrome with tumefactive central nervous system involvement.

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Neurological involvement in Primary Sjögren Syndrome.

OBJECTIVES To perform an observational retrospective cross-sectional case-control study to evaluate prevalence, clinical patterns and outcomes of neurological involvement in a cohort of Primary Sjögren Syndrome (pSS) patients followed up in a single center. MATERIAL AND METHODS From a total of 93 pSS patients, diagnosed according to the 2002 criteria proposed by the American-European Consensu...

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Primary Sjogren's syndrome with central nervous system involvement.

OBJECTIVE To describe the clinical, laboratory, and radiological features of Primary Sjogren's syndrome (PSS) with central nervous system (CNS) involvement. METHODS A retrospective case series of 12 female patients with PSS and CNS involvement at King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia from 1991-2009. The diagnosis of PSS is defined by the American...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0084605